Aspergillosis is caused by Aspergillus fungus which
is present in the soil and decaying material. This
fungus does not affect normal human beings and the
infection is more common among cancer patients
receiving chemotherapy or among transplant patients
on immune suppressive therapy.
The most common sites of infection are the lungs and
sinus. The infection can present from simple allergic to serious invasive forms.
The different forms of infections are
-Allergic bronchopulmonary aspergillosis presenting
-Pulmonary Aspergilloma found in old cases of lung
cavities of tuberculosis and lung absces
-life threatening invasive aspergillosis.
The symptoms are - cough, breathlessness, blood in
sputum, pain in chest or face over the sinus, fever,
and night sweat or meningitis.
Treatment for invasive Aspergillosis:
- several weeks of i.v. FUNGISOME®, this Liposomal
Amphotericin B is a drug of choice along with
- Surgical removal
- Oral Fungitrace® (Itraconazole) should be used